What is the best treatment for low HDL?. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Huber, Brian; Ludwig, Jennifer; Sheridan, Edward; Wyncott, David
• Is Part Of: Evidence-based practice. Volume 18:Issue 2(2015)
• Publication Date: 2015-02
• DOI: 10.1097/01.EBP.0000540903.36787.58
• Languages: English
• ISSNs: 1095-4120

Abstract

Abstract : Evidence‐Based Answer : No high‐quality evidence is available regarding the impact of a low‐fat diet for patients with low high‐density lipoprotein (HDL). Moderate alcohol consumption may slightly increase HDL levels by less than 0.1 mmol/L. Medications including fibrates and HMG‐CoA reductase inhibitors increase HDL by 3% to 10% (SOR: C, disease‐oriented outcomes). In patients with both low HDL and low LDL with cardiovascular risk factors, pravastatin therapy reduces cardiovascular events by 4% over 6 years (SOR: B, RCT).