What interventions improve outcomes for patients with isolated low levels of high‐density lipoprotein cholesterol (HDL‐C)?. Issue 12 (December 2015)

• Record Type: Journal Article
• Authors: Haver, Amy; Irwin, Manasa; Haugh, Amy; Wilson, Stephen A.
• Is Part Of: Evidence-based practice. Volume 18:Issue 12(2015)
• Publication Date: 2015-12
• DOI: 10.1097/01.EBP.0000541118.03131.36
• Languages: English
• ISSNs: 1095-4120

Abstract

Abstract : Evidence‐Based Answer : Niacin, fibrates, and cholesteryl ester transfer protein (CETP) inhibitors may raise HDL, but do not improve cardiovascular outcomes compared with an active comparator (such as a statin). However, niacin and fibrates decrease nonfatal myocardial infarctions (MIs) compared with placebo (SOR: A, meta‐analysis). Exercise alone, diet alone, and a combination of exercise and diet do not increase HDL (SOR: C, metaanalysis with disease‐oriented outcomes).