Review of physical stimulation techniques for assisting distraction osteogenesis in maxillofacial reconstruction applications. (May 2021)

• Record Type: Journal Article
• Authors: Hatefi, Shahrokh; Alizargar, Javad; Le Roux, Francis; Hatefi, Katayoun; Etemadi Sh, Milad; Davids, Hajierah; Hsieh, Nan-Chen; Smith, Farouk; Abou-El-Hossein, Khaled
• Is Part Of: Medical engineering & physics. Volume 91(2021)
• Page Start: 28
• Page End: 38
• Publication Date: 2021-05
• Subjects: Distraction osteogenesis -- Physical stimulation techniques -- Bone healing -- Maxillofacial reconstruction -- Medical devices; Biomedical engineering -- Periodicals; Biomedical Engineering -- Periodicals; Physics -- Periodicals; Génie biomédical -- Périodiques; Biomedical engineering; Electronic journals; Periodicals; 610.28
• DOI: 10.1016/j.medengphy.2021.03.008
• Languages: English
• ISSNs: 1350-4533

Abstract

Highlights: Physical stimulation techniques could successfully assist the bone tissue regeneration during distraction osteogenesis. Physical stimulation techniques could improve the quality of the formed bone tissue and induce bone healing mechanisms. Animal studies have proved the positive effects of applying physical stimulation techniques during distraction osteogenesis. The application of physical stimulation techniques during treatment has different impacts on bone healing mechanisms. Abstract: Distraction Osteogenesis (DO) is an emerging limb lengthening method for the reconstruction of the hard tissue and the surrounding soft tissue, in different human body zones. DO plays an important role in treating bone defects in Maxillofacial Reconstruction Applications (MRA) due to reduced side effects and better formed bone tissue compared to conventional reconstruction methods i.e. autologous bone graft, and alloplast implantation. Recently, varying techniques have been evaluated to enhance the characteristics of the newly formed tissues and process parameters. Promising results have been shown in assisting DO treatments while benefiting bone formation mechanisms by using physical stimulation techniques, including photonic, electromagnetic, electrical, and mechanical stimulation technique. Using assisted DO techniques has provided superior results in the outcome of the DO procedure compared to a standard DO procedure. However, DO methods, as well as assisting technologies applied during the DO procedure, are still emerging. Studies and experiments on developed solutions related to this field have been limited to animal and clinical trials. In this review paper, recent advances in physical stimulation techniques and their effects on the outcome of the DO treatment in MRA are surveyed. By studying the effects of using assisting techniques during the DO treatment, enabling an ideal assisted DO technique in MRA can be possible. Although mentioned techniques have shown constructive effects during the DO procedure, there is still a need for more research and investigation to be done to fully understand the effects of assisting techniques and advanced technologies for use in an ultimate DO procedure in MRA.