Measuring health-related quality of life in chronic headache: A comparative evaluation of the Chronic Headache Quality of Life Questionnaire and Headache Impact Test (HIT-6). (September 2021)

• Record Type: Journal Article
• Authors: Haywood, Kirstie L; Achana, Felix; Nichols, Vivien; Pearce, Gemma; Box, Barbara; Muldoon, Lynne; Patel, Shilpa; Griffiths, Frances; Stewart, Kimberly; Underwood, Martin; Matharu, Manjit M
• Is Part Of: Cephalalgia. Volume 41:Number 10(2021)
• Page Start: 1100
• Page End: 1123
• Publication Date: 2021-09
• Subjects: Headache Impact Test -- psychometric evaluation -- chronic headache -- quality of life -- outcome measures; Headache -- Periodicals; 616.8491
• DOI: 10.1177/03331024211006045
• Languages: English
• ISSNs: 0333-1024

Abstract

Objective: To compare the quality and acceptability of a new headache-specific patient-reported measure, the Chronic Headache Quality of Life Questionnaire (CHQLQ) with the six-item Headache Impact Test (HIT-6), in people meeting an epidemiological definition of chronic headaches. Methods: Participants in the feasibility stage of the Chronic Headache Education and Self-management Study (CHESS) (n = 130) completed measures three times during a 12-week prospective cohort study. Data quality, measurement acceptability, reliability, validity, responsiveness to change, and score interpretation were determined. Semi-structured cognitive interviews explored measurement relevance, acceptability, clarity, and comprehensiveness. Results: Both measures were well completed with few missing items. The CHQLQ's inclusion of emotional wellbeing items increased its relevance to participant's experience of chronic headache. End effects were present at item level only for both measures. Structural assessment supported the three and one-factor solutions of the CHQLQ and HIT-6, respectively. Both the CHQLQ (range 0.87 to 0.94) and HIT-6 (0.90) were internally consistent, with acceptable temporal stability over 2 weeks (CHQLQ range 0.74 to 0.80; HIT-6 0.86). Both measures responded to change in headache-specific health at 12 weeks (CHQLQ smallest detectable change (improvement) range 3 to 5; HIT-6 2.1). Conclusions: While both measures are structurally valid, internally consistent, temporally stable, and responsive to change, the CHQLQ has greater relevance to the patient experience of chronic headache. Trial registration number: ISRCTN79708100. Registered 16th December 2015, http://www.isrctn.com/ISRCTN79708100