Interfering with a memory without erasing its trace. (January 2020)

• Record Type: Journal Article
• Authors: Lange, Gesa; Senden, Mario; Radermacher, Alexandra; De Weerd, Peter
• Is Part Of: Neural networks. Volume 121(2020)
• Page Start: 339
• Page End: 355
• Publication Date: 2020-01
• Subjects: Perceptual learning -- Behavioral interference -- Expert skill -- Early visual cortex -- Tuning curves -- Recurrent neural network; Neural computers -- Periodicals; Neural networks (Computer science) -- Periodicals; Neural networks (Neurobiology) -- Periodicals; Nervous System -- Periodicals; Ordinateurs neuronaux -- Périodiques; Réseaux neuronaux (Informatique) -- Périodiques; Réseaux neuronaux (Neurobiologie) -- Périodiques; Neural computers; Neural networks (Computer science); Neural networks (Neurobiology); Periodicals; 006.32
• DOI: 10.1016/j.neunet.2019.09.027
• Languages: English
• ISSNs: 0893-6080

Abstract

Abstract: Previous research has shown that performance of a novice skill can be easily interfered with by subsequent training of another skill. We address the open questions whether extensively trained skills show the same vulnerability to interference as novice skills and which memory mechanism regulates interference between expert skills. We developed a recurrent neural network model of V1 able to learn from feedback experienced over the course of a long-term orientation discrimination experiment. After first exposing the model to one discrimination task for 3480 consecutive trials, we assessed how its performance was affected by subsequent training in a second, similar task. Training the second task strongly interfered with the first (highly trained) discrimination skill. The magnitude of interference depended on the relative amounts of training devoted to the different tasks. We used these and other model outcomes as predictions for a perceptual learning experiment in which human participants underwent the same training protocol as our model. Specifically, over the course of three months participants underwent baseline training in one orientation discrimination task for 15 sessions before being trained for 15 sessions on a similar task and finally undergoing another 15 sessions of training on the first task (to assess interference). Across all conditions, the pattern of interference observed empirically closely matched model predictions. According to our model, behavioral interference can be explained by antagonistic changes in neuronal tuning induced by the two tasks. Remarkably, this did not stem from erasing connections due to earlier learning but rather from a reweighting of lateral inhibition. Highlights: Skill acquisition in novices can be interfered with by training on another skill. It is unknown whether expert skill can be similarly interfered with. This question is addressed in a recurrent neural network of perceptual learning. The model predicts strong interference even for excessively trained skills. Model predictions are borne out by a series of psychophysical experiments.