Paediatric long term continuous positive airway pressure and noninvasive ventilation in France: A cross-sectional study. (May 2021)

• Record Type: Journal Article
• Authors: Fauroux, Brigitte; Khirani, Sonia; Amaddeo, Alessandro; Massenavette, Bruno; Bierme, Priscille; Taytard, Jessica; Stremler, Nathalie; Baravalle-Einaudi, Melisande; Mazenq, Julie; Ioan, Iulia; Schweitzer, Cyril; Lampin, Marie Emilie; Binoche, Alexandra; Mordacq, Clemence; Bergounioux, Jean; Mbieleu, Blaise; Rubinsztajn, Robert; Sigur, Elodie; Labouret, Geraldine; Genevois, Aline; Becourt, Arnaud; Hullo, Eglantine; Pin, Isabelle; Debelleix, Stéphane; Galodé, François; Bui, Stéphanie; Moreau, Johan; Renoux, Marie Catherine; Matecki, Stefan; Lavadera, Marc Lubrano; Heyman, Rachel; Pomedio, Michael; Le Clainche, Laurence; Bokov, Plamen; Masson, Alexandra; Hangard, Pauline; Menetrey, Celine; Jokic, Mikael; Gachelin, Elsa; Perisson, Caroline; Pervillé, Anne; Fina, Agnes; Giovannini-Chami, Lisa; Fleurence, Emmanuelle; Barzic, Audrey; Breining, Audrey; Ollivier, Morgane; Labbé, Guillaume; Coutier, Laurianne; Aubertin, Guillaume;
• Is Part Of: Respiratory medicine. Volume 181(2021)
• Publication Date: 2021-05
• Subjects: Continuous positive airway pressure -- Noninvasive ventilation -- Home care -- Sleep-disordered breathing -- Obstructive sleep apnea; Chest -- Diseases -- Periodicals; Chest -- Diseases -- Great Britain -- Periodicals; Respiratory organs -- Diseases -- Periodicals; Respiratory Tract Diseases -- Periodicals; Appareil respiratoire -- Maladies -- Périodiques; Thorax -- Maladies -- Périodiques; Appareil respiratoire -- Maladies -- Traitement -- Périodiques; Electronic journals; 616.2
• DOI: 10.1016/j.rmed.2021.106388
• Languages: English
• ISSNs: 0954-6111

Abstract

Abstract: Objective: To describe the characteristics of children treated with long term continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV) in France. Design: Cross-sectional national survey. Setting: Paediatric CPAP/NIV teams of 28 tertiary university hospitals in France. Patients: Children aged <20 years treated with CPAP/NIV since at least 3 months on June 1st, 2019. Intervention: An anonymous questionnaire was filled in for every patient. Results: The data of 1447 patients (60% boys), mean age 9.8 ± 5.8 years were analysed. The most frequent underlying disorders were: upper airway obstruction (46%), neuromuscular disease (28%), disorder of the central nervous system (13%), cardiorespiratory disorder (7%), and congenital bone disease (4%). Forty-five percent of the patients were treated with CPAP and 55% with NIV. Treatment was initiated electively for 92% of children, while 8% started during an acute illness. A poly(somno)graphy (P(S)G) was performed prior to treatment initiation in 26%, 36% had a P(S)G with transcutaneous carbon dioxide monitoring (PtcCO2 ), while 23% had only a pulse oximetry (SpO2 ) with PtcCO2 recording. The decision of CPAP/NIV initiation during an elective setting was based on the apnea-hypopnea index (AHI) in 41% of patients, SpO2 and PtcCO2 in 25% of patients, and AHI with PtcCO2 in 25% of patients. Objective adherence was excellent with a mean use of 7.6 ± 3.2 h/night. Duration of CPAP/NIV was 2.7 ± 2.9 years at the time of the survey. Conclusion: This survey shows the large number of children treated with long term CPAP/NIV in France with numerous children having disorders other than neuromuscular diseases. Highlights: 1447 children were treated with long term CPAP or NIV in France on June 2019. The number of children treated with CPAP or NIV in France has increased 14-fold between 2000 and 2019. The most frequent disorders were upper airway obstruction (46%) and neuromuscular disease (28%). 45% of the children were treated with CPAP and 55% with NIV.