Prevalence of urolithiasis among the Uyghur children of China: a population‐based cross‐sectional study. (7th May 2019)

• Record Type: Journal Article
• Authors: Mai, Zanlin; Liu, Yongda; Wu, Wenqi; Aierken, Ainiwaer; Jiang, Chonghe; Batur, Jesur; Wusiman, Sulitan; Ma, Jinxiang; Li, Yusi; Xu, Hai; Ainiwa, Aikebaier; Saimaiti, Saiding; Tuerxun, Aierken; Zeng, Guohua
• Is Part Of: BJU international. Volume 124:Number 3(2019)
• Page Start: 395
• Page End: 400
• Publication Date: 2019-05-07
• Subjects: prevalence -- urolithiasis -- children -- Uyghur; Genitourinary organs -- Diseases -- Periodicals; Genitourinary organs -- Surgery -- Periodicals; Urology -- Periodicals; 616.6
• DOI: 10.1111/bju.14776
• Languages: English
• ISSNs: 1464-4096

Abstract

Abstract : Objectives: To investigate the prevalence and associated factors of urolithiasis amongst Uyghur children. Subjects and Methods: A cross‐sectional survey was conducted of Uyghur children (aged ≤14 years) in the Kashgar Region of China, from July to December 2016. Children were selected by a two‐stage random clustered sampling method, evaluated by urinary tract ultrasonography, low‐dose computed tomography (CT) examination, blood and urine analysis, and a questionnaire. The prevalence by CT, the prevalence by self‐report in the questionnaires, and the lifetime prevalence were evaluated. Binary logistic regression was used to estimate the associated factors. Results: A total of 5605 children were selected and invited to participate in the study. In all, 4813 Uyghur children (2471 boys and 2342 girls), with an mean (SD; range) age of 75.79 (43.81; 2–177) months, were included in the final analysis, with a response rate of 85.9%. The prevalence of paediatric urolithiasis was 1.8% (95% confidence interval [CI] 1.5–2.2) by CT, 2.3% (95% CI 1.9–2.7) by self‐report, and 3.6% (95% CI 3.0–4.1) for the overall life‐time. The age‐sex adjusted prevalence was 2.0% (95% CI 1.6–2.4) by CT. Binary logistic regression analysis showed that body mass index, urinary tract infection, a family history of urolithiasis, and excessive sweating could increase the risk of stone formation, whilst breast feeding and drinking water at midnight could decrease the risk. Conclusions: Urolithiasis is a major public health problem amongst Uyghur children, and strategies aimed at the prevention of urolithiasis are needed.