Automatic Detection of 2D and 3D Lung Nodules in Chest Spiral CT Scans. (12th February 2013)

• Record Type: Journal Article
• Authors: El-Baz, Ayman; Elnakib, Ahmed; Abou El-Ghar, Mohamed; Gimel'farb, Georgy; Falk, Robert; Farag, Aly
• Other Names: Okada Kazunori Academic Editor.
• Is Part Of: International journal of biomedical imaging. Volume 2013(2013)
• Publication Date: 2013-02-12
• Subjects: Diagnostic imaging -- Periodicals; Imaging systems in medicine -- Periodicals; Imagerie pour le diagnostic; Imagerie médicale; Diagnostic imaging; Imaging systems in medicine; Diagnostic Imaging -- Periodicals; Electronic journals; Periodicals; 616.0754
• DOI: 10.1155/2013/517632
• Languages: English
• ISSNs: 1687-4188

Abstract

Abstract : Automatic detection of lung nodules is an important problem in computer analysis of chest radiographs. In this paper, we propose a novel algorithm for isolating lung abnormalities (nodules) from spiral chest low-dose CT (LDCT) scans. The proposed algorithm consists of three main steps. The first step isolates the lung nodules, arteries, veins, bronchi, and bronchioles from the surrounding anatomical structures. The second step detects lung nodules using deformable 3D and 2D templates describing typical geometry and gray-level distribution within the nodules of the same type. The detection combines the normalized cross-correlation template matching and a genetic optimization algorithm. The final step eliminates the false positive nodules (FPNs) using three features that robustly define the true lung nodules. Experiments with 200 CT data sets show that the proposed approach provided comparable results with respect to the experts.