Oncogenic Brain Metazoan Parasite Infection. (18th September 2013)

• Record Type: Journal Article
• Authors: Spurgeon, Angela N.; Cress, Marshall C.; Gabor, Oroszi; Ding, Qing-Qing; Tanaka, Tomoko; Miller, Douglas C.
• Other Names: Amirjamshidi A. Academic Editor.; Mangano F. T. Academic Editor.; Turgut M. Academic Editor.
• Is Part Of: Case reports in neurological medicine. Volume 2013(2013)
• Publication Date: 2013-09-18
• Subjects: Neurology -- Periodicals; Nervous system -- Diseases -- Periodicals; Neurology; Nervous System Diseases; Nervous system -- Diseases; Neurology; Electronic journals; Periodicals; Periodicals; 616.8
• DOI: 10.1155/2013/263718
• Languages: English
• ISSNs: 2090-6676

Abstract

Abstract : Multiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis, and a WHO grade IV neuroepithelial tumor with exclusively neuronal differentiation by immunohistochemical stains (immunopositive for synaptophysin, neurofilament protein, and Neu-N and not for GFAP, vimentin, or S100). The colocalization and temporal relationship of these two entities suggest a causal relationship.