Ehlers-Danlos Syndrome Type VIII: A Rare Cause of Leg Ulcers in Young Patients. (3rd October 2013)

• Record Type: Journal Article
• Authors: Ronceray, Sophie; Miquel, Juliette; Lucas, Antoine; Piérard, Gérald E.; Hermanns-Lê, Trinh; De Paepe, Anne; Dupuy, Alain
• Other Names: Oiso N. Academic Editor.; Yamamoto T. Academic Editor.
• Is Part Of: Case reports in dermatological medicine. Volume 2013(2013)
• Publication Date: 2013-10-03
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; 616.5005
• DOI: 10.1155/2013/469505
• Languages: English
• ISSNs: 2090-6463

Abstract

Abstract : Ehlers-Danlos syndrome type VIII (EDS-VIII) is a very rare autosomal dominant disease characterized by early-onset periodontitis associated with features of Ehlers-Danlos syndrome. We report a 32-year-old man whose chronic leg ulcer led to the diagnosis of EDS-VIII. He had severe periodontitis with complete loss of permanent teeth and skin fragility with thin skin, atrophic scars, and brownish atrophic pretibial plaques. Leg ulcer is not a prominent feature of EDS-VIII. We suggest adding EDS-VIII to the list of rare diseases accounting for chronic leg ulcers, if this case report prompts others to report leg ulcers associated with EDS-VIII.