BRAF V600E-Negative Hairy Cell Leukaemia. (9th April 2013)

• Record Type: Journal Article
• Authors: Langabeer, Stephen E.; O'Brien, David; McElligott, Anthony M.; Lavin, Michelle; Browne, Paul V.
• Other Names: Arellano-Rodrigo E. Academic Editor.; Pihan G. Academic Editor.; Rund D. Academic Editor.; Wagner S. D. Academic Editor.
• Is Part Of: Case reports in hematology. Volume 2013(2013)
• Publication Date: 2013-04-09
• Subjects: Hematology -- Periodicals; Hematology -- Case studies -- Periodicals; Blood -- Diseases -- Periodicals; Hematology; Hematologic Diseases; Blood -- Diseases; Hematology; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.15
• DOI: 10.1155/2013/513049
• Languages: English
• ISSNs: 2090-6560

Abstract

Abstract : Since the initial report of the BRAF V600E mutation in hairy cell leukemia, numerous investigators have demonstrated the presence of this activating mutation in nearly all cases of this disease. A case of hairy cell leukemia is documented with a classical clinical, morphological, immunophenotypic, and cytochemical profile in which the BRAF V600E was not detected. The diagnostic and therapeutic implications are discussed.