Primary Cutaneous Mantle Cell Lymphoma: A Case Report. (23rd May 2013)

• Record Type: Journal Article
• Authors: Mazzuoccolo, L. D.; Castro Perez, G. A.; Sorin, I.; Bravo, A. I.
• Other Names: Cuevas-Covarrubias S. A. Academic Editor.; Jinnin M. Academic Editor.; Kawara S. Academic Editor.; Oiso N. Academic Editor.
• Is Part Of: Case reports in dermatological medicine. Volume 2013(2013)
• Publication Date: 2013-05-23
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; 616.5005
• DOI: 10.1155/2013/394596
• Languages: English
• ISSNs: 2090-6463

Abstract

Abstract : Primary cutaneous mantle cell lymphoma (MCL) is a rare cutaneous proliferation of naive pregerminal CD-5 positive B cells in the skin with no extracutaneous involvement. Overexpression of cyclin D1 is pathognomonic of this condition, and surgery and radiation therapy are the most common therapeutic options. In this case, we describe the clinical, histopathological, immunohistochemical, and molecular characteristics of a new case of primary cutaneous MCL.