Amelanotic Melanoma Masquerading as a Granular Cell Lesion. (25th February 2013)

• Record Type: Journal Article
• Authors: Pandiar, Deepak; Basheer, Shaini; Shameena, P. M.; Sudha, S.; Dhana, Lakshmi J.
• Other Names: El-Hakim I. Academic Editor.; Sayin M. O. Academic Editor.; Yarom N. Academic Editor.
• Is Part Of: Case reports in dentistry. Volume 2013(2013)
• Publication Date: 2013-02-25
• Subjects: Dentistry -- Case studies -- Periodicals; Oral medicine -- Case studies -- Periodicals; Oral Medicine; Dentistry; Dentistry; Oral medicine; Electronic journals; Periodical; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 617.6
• DOI: 10.1155/2013/924573
• Languages: English
• ISSNs: 2090-6447

Abstract

Abstract : Amelanotic melanoma (AM) presents a diagnostic challenge due to its wide clinical presentations, lack of pigmentation, and varied histological appearances. Immunohistochemistry plays a crucial role in the diagnosis of these lesions. Amelanotic melanoma of oral mucosa is an uncommon lesion. We report a case of a 50-year-old male patient with a growth on the anterior mandibular gingiva of seven-month duration. In the present case, histologically, the tumour resembled a granular cell lesion, which has not been reported previously in AM. Diagnosis was possible by a sequential panel of immunohistochemical markers, of which finally vimentin, S100, HMB45, and Melan-A were positive. The tumor was surgically excised, and postsurgical radiotherapy was given.