Clinical Applications of Remote Ischemic Preconditioning. (14th February 2012)

• Record Type: Journal Article
• Authors: Veighey, Kristin; MacAllister, Raymond J.
• Other Names: Tsui Janice Academic Editor.
• Is Part Of: Cardiology research and practice. Volume 2012(2012)
• Publication Date: 2012-02-14
• Subjects: Cardiology -- Research -- Periodicals; Cardiology -- Periodicals; Cardiology; Cardiology; Cardiology -- Research; Electronic journals; Periodicals; Periodicals; 616.12
• DOI: 10.1155/2012/620681
• Languages: English
• ISSNs: 2090-8016

Abstract

Abstract : Ischemia-reperfusion injury is a composite of damage accumulated during reduced perfusion of an organ or tissue and the additional insult sustained during reperfusion. Such injury occurs in a wide variety of clinically important syndromes, such as ischemic heart disease and stroke, which are responsible for a high degree of morbidity and mortality worldwide. Basic research has identified a number of interventions that stimulate innate resistance of tissues to ischemia-reperfusion injury. Here, we summarise the experimental and clinical trial data underpinning one of these "conditioning" strategies, the phenomenon of remote ischemic preconditioning.