Factors Influencing Women's Decision to Participate or Not in a Surgical Randomised Controlled Trial for Surgical Treatment of Female Stress Urinary Incontinence. (17th September 2013)

• Record Type: Journal Article
• Authors: Mostafa, Alyaa; N'Dow, James; Abdel-Fattah, Mohamed
• Other Names: Zeigler-Johnson Charnita M. Academic Editor.
• Is Part Of: BioMed research international. Volume 2013(2013)
• Publication Date: 2013-09-17
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2013/139813
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : The study aims to explore the potentially influential factors affecting women's decision to accept/decline participation in surgical randomised trial using a novel acceptance/refusal questionnaire (ARQ). All women who were eligible to participate in SIMS-RCT were asked to complete the relevant section (acceptance/refusal) of the ARQ. Women reported its degree of relevance for their decision on a six-point Likert scale (0 = highly irrelevant, 5 = highly relevant). 135 (98%) and 31 (70%) women completed the acceptance and refusal sections of the ARQ, respectively. The most influencing factor in women's acceptance was the anticipation of "potential personal benefit"; percentage of relevance (POR) was 91.9%, followed by interest in helping others by "supporting innovative medical research"; POR was 87.7%. Most influencing factor in refusal for participation was "do not have time for follow-up"; POR was 56.8%, followed by "do not like the concept of randomisation"; POR was 54.4%. In conclusion, this study identifies the most influential factors relevant to women decision-making whether or not to participate in RCTs assessing surgical interventions for female stress urinary incontinence (SUI). A number of factors leading to refusal of participation are potentially correctable leading to better recruitment rates in future RCTs.