A Randomized Controlled Trial of Two Different Lengths of Nicotine Replacement Therapy for Smoking Cessation. (9th September 2013)

• Record Type: Journal Article
• Authors: Abdullah, Abu S.; Hedley, Anthony J.; Chan, Sophia S. C.; Lam, Tai-Hing
• Other Names: Ma Ronald Academic Editor.
• Is Part Of: BioMed research international. Volume 2013(2013)
• Publication Date: 2013-09-09
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2013/961751
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : This study examined if 2-week free nicotine replacement therapy (NRT) would be more effective than 1-week free NRT to help smokers quit smoking at 6 and 12 months. In a single-blinded randomized controlled trial design, 562 Chinese smokers who attended a smoking cessation clinic in Hong Kong, China, were randomly allocated into two groups (A1 and A2): A1 (n = 284 ) received behavioural counselling with free NRT for 1 week; A2 (n = 278 ) received similar counselling with free NRT for 2 weeks. All subjects received printed self-help materials to support their quitting efforts. A structured questionnaire was used for data collection, including pattern of NRT use and self-reported 7-day point prevalence quit rate at 6 months and 12 months. Among the participants, the mean number of cigarettes smoked per day was 18.8 (S D = 10.9 ). By intention-to-treat analysis, 7-day point prevalence quit rates were not significantly different between A1 and A2 groups at 6-month (27.5% versus 27.3%; P = 0.97 ) and 12-month (21.1% versus 21.2%; P = 0.98 ) followup. The findings suggest that two-week free NRT was not more effective than 1-week free NRT to increase smoking cessation rate among Chinese smokers.