Recurrent Transient Ischemic Attacks in a Patient with POEMS Syndrome. (4th March 2014)

• Record Type: Journal Article
• Authors: Akyol, A.; Nazliel, B.; Batur Caglayan, H. Z.; Oner, Y.; Sucak, G. Turkoz
• Other Names: Fee D. B. Academic Editor.; González-Gutiérrez J. L. Academic Editor.; Hashimoto R. Academic Editor.
• Is Part Of: Case reports in neurological medicine. Volume 2014(2014)
• Publication Date: 2014-03-04
• Subjects: Neurology -- Periodicals; Nervous system -- Diseases -- Periodicals; Neurology; Nervous System Diseases; Nervous system -- Diseases; Neurology; Electronic journals; Periodicals; Periodicals; 616.8
• DOI: 10.1155/2014/158471
• Languages: English
• ISSNs: 2090-6676

Abstract

Abstract : A 47-year-old female with a prior history of POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome was admitted with transient ischemic attacks complicated by dysarthria and right-sided hemiparesis. A blood survey indicated thrombocytosis and hyperfibrinogenemia while imaging of intracranial vasculature showed occlusion of the bilateral middle cerebral arteries. POEMS syndrome, of which arterial thromboses have been mentioned as a manifestation, is rarely accompanied by transient ischemic attacks. The pathophysiologic mechanism is yet unclear and needs further investigation.