Development of temperature dependent oxygen releasable nanofilm by modulating oxidation state of myoglobin. Issue 42 (14th May 2021)

• Record Type: Journal Article
• Authors: Tomioka, Daisuke; Nakatsuji, Hirotaka; Miyagawa, Shigeru; Sawa, Yoshiki; Matsusaki, Michiya
• Is Part Of: Chemical communications. Volume 57:Issue 42(2021)
• Page Start: 5131
• Page End: 5134
• Publication Date: 2021-05-14
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d1cc01545a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Temperature dependent controlled oxygen release from oxymyoglobin was achieved by modulating autoxidation of oxymyoglobin using ascorbic acid as a reductant. Abstract : Controlled release of oxygen from myoglobin was achieved by modulating autoxidation of oxymyoglobin using ascorbic acid as a reductant by temperature variation. Long-term storage, prompt release and re-storage of oxygen were also available with this system. Furthermore, 20 nm thick nanofilms composed of oxymyoglobin and type I collagen containing ascorbic acid could successfully show autoxidation of oxymyoglobin in response to environmental temperature. The ultrathin nanofilms will be useful as oxygen-controlled releasable scaffolds for tissue engineering application.