Multiple testing: when is many too much?. Issue 3 (March 2021)

• Record Type: Journal Article
• Authors: Groenwold, Rolf H H; Goeman, Jelle J; Cessie, Saskia Le; Dekkers, Olaf M
• Is Part Of: European journal of endocrinology. Volume 184:Issue 3(2021)
• Page Start: E11
• Page End: E14
• Publication Date: 2021-03
• Subjects: Endocrinology -- Periodicals; 616.4005
• DOI: 10.1530/EJE-20-1375
• Languages: English
• ISSNs: 0804-4643

Abstract

Abstract : In almost all medical research, more than a single hypothesis is being tested or more than a single relation is being estimated. Testing multiple hypotheses increases the risk of drawing a false-positive conclusion. We briefly discuss this phenomenon, which is often called multiple testing. Also, methods to mitigate the risk of false-positive conclusions are discussed.