Does a brief trial of endotracheal CPAP before extubation increase the work of breathing in preterm infants?. (June 2021)

• Record Type: Journal Article
• Authors: Vervenioti, Aggeliki; Dassios, Theodore; Sinopidis, Xenophon; Dimitriou, Gabriel
• Is Part Of: Early human development. Volume 157(2021)
• Publication Date: 2021-06
• Subjects: Mechanical ventilation -- Premature infants -- Weaning -- Work of breathing -- Extubation -- Spontaneous breathing trial; Fetus -- Periodicals; Neonatology -- Periodicals; Prenatal influences -- Periodicals; 612.65
• DOI: 10.1016/j.earlhumdev.2021.105368
• Languages: English
• ISSNs: 0378-3782

Abstract

Abstract: A brief period of endotracheal continuous positive airway pressure (ETT-CPAP) can predict extubation outcome but longer periods are associated with increased work of breathing and extubation failure. In ventilated preterm infants, brief ETT-CPAP does not increase the work of breathing and can be used to predict the outcome of extubation. Highlights: A brief period of endotracheal continuous positive airway pressure (ETT-CPAP) can predict extubation outcome in preterms. ETT-CPAP could potentially increase the work of breathing. ETT-CPAP before extubation does not increase the work of breathing compared to low rate synchronised mechanical ventilation.