Diet quality at age 5–6 and cardiovascular outcomes in preadolescents. (June 2021)

• Record Type: Journal Article
• Authors: Krijger, JJ. Anne; Nicolaou, Mary; Nguyen, Anh N.; Voortman, Trudy; Hutten, Barbara A.; Vrijkotte, Tanja GM.
• Is Part Of: Clinical nutrition ESPEN. Volume 43(2021)
• Page Start: 506
• Page End: 513
• Publication Date: 2021-06
• Subjects: Diet quality -- DASH diet -- Childhood nutrition -- Cardiovascular risk -- Longitudinal cohort study; ABCD Amsterdam Born Children and their Development -- FFQ food frequency questionnaire -- CDQS Child Diet Quality Score -- DASH Dietary Approaches to Stop Hypertension -- CIMT carotid intima-media thickness; Nutritionally induced diseases -- Periodicals; Metabolism -- Disorders -- Periodicals; 616.39005
• DOI: 10.1016/j.clnesp.2021.02.011
• Languages: English
• ISSNs: 2405-4577

Abstract

Summary: Background & aims: Specific dietary components during childhood may affect risk factors for cardiovascular disease. Whether overall higher diet quality prevents children from adverse cardiovascular outcomes remains contradictive. We aimed to examine the associations between diet quality at age 5–6 years and cardiovascular outcomes after a 6-year follow-up. Methods: We used data from the Amsterdam Born Children and their Development study, a multi-ethnic birth cohort. Dietary intake was assessed at age 5–6 using a semi-quantitative food frequency questionnaire and diet quality was ascertained with the Dietary Approaches to Stop Hypertension (DASH) score and the child diet quality score (CDQS), an index specifically developed for Dutch school-age children. Cardiovascular outcomes were examined after 6-years follow-up (age 11–12, N = 869). Outcomes were body mass index (BMI), waist circumference (WC), blood pressure (BP), lipid profile, fasting glucose and carotid intima-media thickness (CIMT). Multivariable linear and logistic regression models adjusted for baseline value were used to examine associations between diet quality and cardiovascular outcomes. Results: Higher diet quality at age 5–6 was associated with lower BMI (DASH score: Δ quintile (Q) 5 and Q1: −0.35 kg/m 2, p for trend = 0.016), lower WC (DASH score: Δ Q5 and Q1: −1.0 cm, p for trend = 0.028), lower systolic (DASH score: Δ Q5 and Q1: −2.7 mmHg, p for trend = 0.046) and diastolic BP (DASH score: Δ Q5 and Q1: −2.4, p for trend < 0.001) and with lower plasma triglycerides (DASH score: Δ Q5 and Q1: −0.20 mmol/L, p for trend = 0.032) after 6-years follow-up. Associations of the CDQS with these outcomes showed similar trends, but less pronounced. We found no statistically significant associations between diet quality and LDL-C, HDL-C, total cholesterol, fasting glucose or CIMT. Conclusions: Higher diet quality in childhood at age 5–6 years predicted better health on some cardiovascular outcomes in preadolescence.