Vaccine-associated enhanced disease: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data. Issue 22 (21st May 2021)

• Record Type: Journal Article
• Authors: Munoz, Flor M.; Cramer, Jakob P.; Dekker, Cornelia L.; Dudley, Matthew Z.; Graham, Barney S.; Gurwith, Marc; Law, Barbara; Perlman, Stanley; Polack, Fernando P.; Spergel, Jonathan M.; Van Braeckel, Eva; Ward, Brian J.; Didierlaurent, Arnaud M.; Lambert, Paul Henri
• Is Part Of: Vaccine. Volume 39:Issue 22(2021)
• Page Start: 3053
• Page End: 3066
• Publication Date: 2021-05-21
• Subjects: Adverse event -- Immunization -- Guidelines -- Case definition -- Vaccine -- Enhanced disease -- Respiratory -- Systemic disease; Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2021.01.055
• Languages: English
• ISSNs: 0264-410X

Abstract

Abstract: This is a Brighton Collaboration Case Definition of the term "Vaccine Associated Enhanced Disease" to be utilized in the evaluation of adverse events following immunization. The Case Definition was developed by a group of experts convened by the Coalition for Epidemic Preparedness Innovations (CEPI) in the context of active development of vaccines for SARS-CoV-2 vaccines and other emerging pathogens. The case definition format of the Brighton Collaboration was followed to develop a consensus definition and defined levels of certainty, after an exhaustive review of the literature and expert consultation. The document underwent peer review by the Brighton Collaboration Network and by selected Expert Reviewers prior to submission.