Investigating the Relationship between Topology and Evolution in a Dynamic Nematode Odor Genetic Network. (28th September 2012)

• Record Type: Journal Article
• Authors: Fitzpatrick, David A.; O'Halloran, Damien M.
• Other Names: Joshi Amitabh Academic Editor.
• Is Part Of: International journal of evolutionary biology. Volume 2012(2012)
• Publication Date: 2012-09-28
• Subjects: Evolution (Biology) -- Periodicals; Biological Evolution; Biological Phenomena; Evolution (Biology); Electronic journals; Periodical; Fulltext; Internet Resources; Periodicals; Periodicals; 576.805
• DOI: 10.1155/2012/548081
• Languages: English
• ISSNs: 2090-8032

Abstract

Abstract : The relationship between biological network architectures and evolution is unclear. Within the phylum nematoda olfaction represents a critical survival tool. For nematodes, olfaction contributes to multiple processes including the finding of food, hosts, and reproductive partners, making developmental decisions, and evading predators. Here we examine a dynamic nematode odor genetic network to investigate how divergence, diversity, and contribution are shaped by network topology. Our findings describe connectivity frameworks and characteristics that correlate with molecular evolution and contribution across the olfactory network. Our data helps guide the development of a robust evolutionary description of the nematode odor network that may eventually aid in the prediction of interactive and functional qualities of novel nodes.