Antiviral activity by lecithin-induced fengycin lipopeptides as a potent key substrate against Cucumber mosaic virus. (June 2021)

• Record Type: Journal Article
• Authors: Kang, Beom Ryong; Park, Joon Seong; Jung, Woo-Jin
• Is Part Of: Microbial pathogenesis. Volume 155(2021)
• Publication Date: 2021-06
• Subjects: Bacillus amyloliquefaciens PPL -- Cucumber mosaic virus -- Lipopeptides -- Nutritional substrate -- Pepper; Pathogenic microorganisms -- Periodicals; Pathology, Molecular -- Periodicals; Communicable Diseases -- microbiology -- Periodicals; Communicable Diseases -- parasitology -- Periodicals; Micro-organismes pathogènes -- Périodiques; Pathologie moléculaire -- Périodiques; Electronic journals; 616.9041
• DOI: 10.1016/j.micpath.2021.104910
• Languages: English
• ISSNs: 0882-4010

Abstract

Abstract: In this study, the effect of different growth substrates on the production of biosurfactants in the PPL strain of Bacillus amyloliquefaciens— a biocontrol agent for diseases affecting pepper and tomato plants — and on the antiviral effect of the PPL strain on Cucumber mosaic virus (CMV)-infected pepper plants was investigated. The multifunctional PPL strain exhibited enhanced growth and increased production of biosurfactants upon lecithin supplementation and consequently exhibited potent anti-CMV activity. The enhanced anti-CMV activity of the lecithin-supplemented PPL culture could be attributed to the antiviral effect as well as to the upregulation of plant defense-related genes. Treatment with pure commercial fengycins elicited a defense response against CMV in pepper plants; this effect was similar to that observed upon treatment with the lecithin-supplemented PPL culture. To the best of our knowledge, this is the first study to report the antiviral activity of lecithin-induced fengycin lipopeptides. These results suggest that the growth substrate affects antimicrobial production by B. amyloliquefaciens PPL, and consequently its antiviral activity. Highlights: The culture medium upon lecithin supplementation improved the biomass and functions of Bacillus amyloliquefaciens PPL. The lecithin-induced fengycin lipopeptides suppressed the development of CMV in pepper plants. Bioactive peptides of fengycin contributed to the elicited defense response potential against CMV.