Tricuspid valvuloplasty for isolated tricuspid regurgitation in children. (25th August 2020)

• Record Type: Journal Article
• Authors: Wang, Guanxi; Ma, Kai; Pang, Kunjing; Zhang, Sen; Qi, Lei; Yang, Yang; Feng, Zicong; Mao, Fengqun; Yuan, Jianhui; Zhang, Hao; Li, Shoujun
• Is Part Of: Cardiology in the young. Volume 30:Number 8(2020)
• Page Start: 1076
• Page End: 1080
• Publication Date: 2020-08-25
• Subjects: Tricuspid regurgitation, -- tricuspid valvuloplasty, -- leaflet cleft, -- CHDs; Pediatric cardiology -- Periodicals; 618.9212
• DOI: 10.1017/S104795112000150X
• Languages: English
• ISSNs: 1047-9511

Abstract

Abstract: Background: Isolated congenital tricuspid regurgitation other than Ebstein's anomaly was rare especially for children. The objective of this study was to investigate the clinical characteristics and to assess the results of tricuspid valvuloplasty for children with isolated tricuspid regurgitation. Methods: From January 2010 to June 2019, 10 consecutive patients with isolated tricuspid regurgitation who were unresponsive to drug therapy underwent tricuspid valvuloplasty in our hospital. Patients' clinical data were analysed retrospectively. Results: Mean age at operation was 48.5 ± 31.0 (range: 9–106) months and mean weight at operation was 16.1 ± 6.9 (range: 8.6–33.0) kg. All patients presented severe isolated tricuspid regurgitation. According to pathological lesions, the main causes accounted for chordae tendinea rupture (3/10), leaflet cleft (2/10), mal-connected chordal tendinea to leaflets (2/10), elongated chordae (1/10) and chordae absent (1/10), and severe anterior leaflet dysplasia (1/10). Individualised tricuspid valvuloplasty was adapted to all of them successfully. Post-operative echocardiography showed no tricuspid regurgitation in two patients and mild regurgitation in eight patients. The cardiothoracic ratios on their chest roentgenograms decreased from 0.59 ± 0.05 to 0.54 ± 0.05. At the latest follow-up (50.4 ± 47.2 months), echocardiography showed that mild to moderate tricuspid regurgitation in seven patients, moderate tricuspid regurgitation in three patients, and no patient with severe tricuspid regurgitation. All patients were in NYHA functional class I. Conclusions: For patients with isolated tricuspid regurgitation who were not well responsive to drug therapy, individualised tricuspid valve repair can achieve an excellent result.