Congenital ductus arteriosus aneurysm in association with MYH11 mutation: a case report. (9th January 2020)

• Record Type: Journal Article
• Authors: Ardhanari, Mohanageetha; Swaminathan, Sethuraman
• Is Part Of: Cardiology in the young. Volume 30:Number 1(2020)
• Page Start: 123
• Page End: 125
• Publication Date: 2020-01-09
• Subjects: Ductus arteriosus aneurysm, -- patent ductus arteriosus, -- connective tissue disorder; Pediatric cardiology -- Periodicals; 618.9212
• DOI: 10.1017/S1047951119003287
• Languages: English
• ISSNs: 1047-9511

Abstract

Abstract: Congenital ductus arteriosus aneurysms develop in the third trimester of fetal life, possibly due to abnormal intimal cushion formation or elastin expression in the ductal wall. It is often diagnosed in infants before 2 months of age. Most have a benign course and resolve spontaneously. However, life-threatening complications have been reported. We report a case of large ductal aneurysm diagnosed incidentally in a neonate, in whom there was a novel mutation in the smooth muscle myosin protein gene— MYH11 .