Amnesia in your pupils: decreased pupil size during autobiographical retrieval in a case of retrograde amnesia. Issue 2 (4th March 2021)

• Record Type: Journal Article
• Authors: El Haj, Mohamad; Lamy, Estelle; Janssen, Steve M. J.; Boutoleau-Bretonnière, Claire
• Is Part Of: Neurocase. Volume 27:Issue 2(2021)
• Page Start: 155
• Page End: 159
• Publication Date: 2021-03-04
• Subjects: Amnesia -- autobiographical memory -- retrograde amnesia -- pupil size -- pupillometry; Neurology -- Periodicals; Neuropsychology -- Case Report; Mental Disorders -- Case Report; Nervous System Diseases -- Case Report; 616.8
• DOI: 10.1080/13554794.2021.1902539
• Languages: English
• ISSNs: 1355-4794

Abstract

ABSTRACT: We investigate whether retrograde-amnesia can be indexed with pupil activity. We present the case of L, 19-year-old, without neurological or psychiatric disorders except for retrograde-amnesia. We invited L to retrieve retrograde and anterograde memories while his pupil size was monitering with eye-tracking glasses. Results demonstrated impaired retrograde retrieval but successful anterograde retrieval in L. He also attributed lower emotional value and visual imagery to his retrograde compared to his anterograde memories. Critically, smaller pupils were observed during retrograde than during anterograde retrieval. Our study provides the first evidence on the value of pupillometry as a potential physiological marker of amnesia.