Minor alkaloids from an aqueous extract of the hook-bearing stem of Uncaria rhynchophylla. Issue 6 (3rd June 2021)

• Record Type: Journal Article
• Authors: Li, Ruo-Fei; Zhu, Cheng-Gen; Xu, Cheng-Bo; Guo, Qing-Lan; Shi, Jian-Gong
• Is Part Of: Journal of Asian natural products research. Volume 23:Issue 6(2021)
• Page Start: 513
• Page End: 526
• Publication Date: 2021-06-03
• Subjects: Indoloquinolizidine alkaloid -- monoterpene alkaloid -- Rubiaceae -- Uncaria rhynchophylla -- uncarrhynchophylline -- uncarrhynchoside; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2021.1906658
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Seven new monoterpene alkaloids (1 −7 ), along with 18 known analogues, were isolated from an aqueous decoction of the hook-bearing stems of Uncaria rhynchophylla (Gou-teng). Their structures were determined by spectroscopic data analysis and electronic circular dichroism (ECD) calculations. Compound 1 is the first monoterpene 22-norindoloquinolizidine alkaloid with a ketene unit, while 2 and 3 are unusual indoloquinolizidine alkaloids having an oxazinane ring.