Bioinspired self-degradable hydrogels towards wound sealing. (5th May 2021)

• Record Type: Journal Article
• Authors: Cao, Qingchen; Sun, Guofei; Wang, Xing; Yang, Fei; Zhang, Licheng; Wu, Decheng
• Is Part Of: Biomaterials science. Volume 9:Number 10(2021)
• Page Start: 3645
• Page End: 3649
• Publication Date: 2021-05-05
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1039/d1bm00420d
• Languages: English
• ISSNs: 2047-4830

Abstract

Abstract : A self-degradable hydrogel was developed as a medical adhesive for skin wounds. The rapid gelation and self-degradation of the hydrogel were achieved via the Michael addition and subsequent hydrolysis of the addition product. Abstract : Inspired by the autolysis of shaggy mane, we developed a self-degradable hydrogel as a medical adhesive for skin wounds. The rapid gelation and self-degradation of the hydrogel were achieved via the Michael addition and subsequent hydrolysis of the addition product. In vivo experiments further showed that the hydrogel adhesive was efficiently applied for skin wound repair.