Asymmetric synthesis of the two enantiomers of β-phosphorus-containing α-amino acids via hydrophosphinylation and hydrophosphonylation of chiral Ni(ii)-complexes. Issue 10 (1st March 2021)

• Record Type: Journal Article
• Authors: Tokairin, Yoshinori; Konno, Hiroyuki; Noireau, Angéline; West, Caroline; Moriwaki, Hiroki; Soloshonok, Vadim A.; Nicolas, Cyril; Gillaizeau, Isabelle
• Is Part Of: Organic chemistry frontiers. Volume 8:Issue 10(2021)
• Page Start: 2190
• Page End: 2195
• Publication Date: 2021-03-01
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d1qo00159k
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A new approach for the synthesis of the two enantiomers of β-phosphorus-containing α-amino acids was developed via Michael addition of secondary phosphine oxides and dialkyl phosphites to chiral Ni(ii )-complexes of a dehydroalanine-Schiff base. Abstract : A new approach for the asymmetric synthesis of the two enantiomers of β-phosphorus-containing α-amino acids was developed via Michael addition of secondary phosphine oxides and dialkyl phosphites to chiral Ni(ii )-complexes of a dehydroalanine-Schiff base.