Prevalence and Associated Metabolic Factors of Gallstone Disease in the Elderly Agricultural and Fishing Population of Taiwan. (23rd February 2014)

• Record Type: Journal Article
• Authors: Shen, Hsi-Che; Hu, Yi-Chun; Chen, Yu-Fen; Tung, Tao-Hsin
• Other Names: Shaffer Eldon A. Academic Editor.
• Is Part Of: Gastroenterology research and practice. Volume 2014(2014)
• Publication Date: 2014-02-23
• Subjects: Gastroenterology -- Periodicals; Digestive organs -- Diseases -- Periodicals; 616.33005
• DOI: 10.1155/2014/876918
• Languages: English
• ISSNs: 1687-6121

Abstract

Abstract : Purpose . To evaluate sex-related differences in the prevalence of and cardiovascular risk factors related to gallstone disease (GSD) in an elderly agricultural and fishing population of Taipei, Taiwan. Methods . The study sample consisted of 6511 healthy elderly participants (3971 men and 2540 women) who were voluntarily admitted to a teaching hospital for a physical checkup in 2010. The participants' blood samples and real-time ultrasound fatty liver results were collected. Results . The prevalence of GSD in the study population was 13.2%, which increased significantly with population age (P < . 0001 ). Women were associated with significantly higher GSD prevalence than men (14.8% versus 12.2%; for the chi-square test, P = . 003 ). In a multiple logistic regression analysis, female sex, older age, and metabolic syndrome (MetS) were significantly associated with GSD. Multiple logistic regression analysis also revealed that obesity (odds ratio O R = 1.26, 95% confidence interval (CI): 1.09–1.44) and metabolic factors (one or 2 versus none, O R = 1.48, 95% CI: 1.08–1.76) were significantly associated with GSD in women but not in men. Conclusion . In the study population, female sex, older age, and MetS were associated with higher GSD prevalence. The population exhibited other sex-related differences.