Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass. (11th September 2013)

• Record Type: Journal Article
• Authors: Moloney, Fiachra; Twomey, Maria; Hinchion, John; Maher, Michael
• Other Names: Byrd R. P. Academic Editor.; Chakera T. Academic Editor.; Fukukura Y. Academic Editor.; Hiwatashi A. Academic Editor.
• Is Part Of: Case reports in radiology. Volume 2013(2013)
• Publication Date: 2013-09-11
• Subjects: Radiology -- Periodicals; Radiology -- Case studies -- Periodicals; Medical radiology -- Periodicals; Radiology; Radiology; Medical radiology; Periodicals; Electronic journals; Case studies; Periodicals; 616.0757
• DOI: 10.1155/2013/130515
• Languages: English
• ISSNs: 2090-6862

Abstract

Abstract : Castleman disease (CD) is a rare benign lymphoproliferative disorder, the etiology of which is unclear. Clinically it may manifest as localized disease (unicentric) or disseminated disease (multicentric). CD occurs in the thorax in 70% of cases, abdomen and pelvis in 15%, and in the neck in 10–15% of cases. We present a case of a pleural mass located posteriorly in a paraspinal location, which was discovered incidentally in a 50-year-old man and was subsequently resected followed by an unexpected diagnosis of Castleman disease on histological examination. In this report, we review the clinical and histological findings in a rare presentation of Castleman disease and discuss the findings in this case as part of an overall review of the typical radiological findings seen in Castleman disease.