Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine. (2nd December 2012)

• Record Type: Journal Article
• Authors: Bajorek, Sarah; Basaldua, Roel; McGoogan, Katherine; Miller, Charla; Sussman, Craig B.
• Other Names: Barbi E. Academic Editor.; Ehlayel M. Academic Editor.; Lee A. C. Academic Editor.; Mohta A. Academic Editor.; Moschovi M. Academic Editor.; Scaramuzza A. E. Academic Editor.; Soliman A. T. Academic Editor.
• Is Part Of: Case reports in pediatrics. Volume 2012(2012)
• Publication Date: 2012-12-02
• Subjects: Pediatrics -- Periodicals; Pediatrics; Pediatrics; Electronic journals; Periodicals; Case Reports; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 618.92
• DOI: 10.1155/2012/412412
• Languages: English
• ISSNs: 2090-6803

Abstract

Abstract : Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel rest and intravenous fluids, is the most common treatment regimen for uncomplicated GLB. Surgical measures are reserved for the rare complications of obstruction and/or perforation. Although limited, utilization of the protein-cleaving enzyme N-acetylcysteine has been described for the disintegration of GLB in toddlers. In this paper, we discuss the first documented use of N-acetylcysteine for a neonatal GLB. Supporting literature, the infant's unusual presentation, and details of the treatment regimen are discussed.