Solitary Polypoid Laryngeal Xanthoma. (20th May 2013)

• Record Type: Journal Article
• Authors: Vera-Sempere, Francisco; Collado-Martín, Diego; Vera-Sirera, Beatriz
• Other Names: Hwang C. F. Academic Editor.; Issing W. Academic Editor.; Morshed K. Academic Editor.
• Is Part Of: Case reports in otolaryngology. Volume 2013(2013)
• Publication Date: 2013-05-20
• Subjects: Otolaryngology -- Periodicals; Otolaryngology -- Case studies -- Periodicals; Otolaryngology; Otorhinolaryngologic Diseases; Otolaryngology; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 617.51
• DOI: 10.1155/2013/967536
• Languages: English
• ISSNs: 2090-6765

Abstract

Abstract : We report the case of a 51-year-old male smoker with diabetes mellitus and hyperlipidaemia and a long history of human immunodeficiency virus (HIV)/hepatitis C virus (HCV) infection treated with various antiretroviral regimes, who was referred to the otolaryngology department with progressive dysphonia. Fibre-optic laryngoscopy showed a solitary, yellowish-white pedunculated polyp on the anterior third of the left cord, with no other abnormality. Pathological analysis revealed a polypoid laryngeal xanthoma that was immunoreactive against CD68, perilipin, and adipophilin. This unusual laryngeal lesion in the clinical context of our patient suggests a possible role of antiretroviral treatment in the pathogenesis of these xanthomas.