Nanomedicines for Endometriosis: Lessons Learned from Cancer Research. Issue 7 (25th January 2021)

• Record Type: Journal Article
• Authors: Moses, Abraham S.; Demessie, Ananiya A.; Taratula, Olena; Korzun, Tetiana; Slayden, Ov D.; Taratula, Oleh
• Is Part Of: Small. Volume 17:Issue 7(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-01-25
• Subjects: endometriosis -- imaging -- nanomedicines -- nanoparticles -- therapies; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.202004975
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract: Endometriosis is an incurable gynecological disease characterized by the abnormal growth of endometrium‐like tissue, characteristic of the uterine lining, outside of the uterine cavity. Millions of people with endometriosis suffer from pelvic pain and infertility. This review aims to discuss whether nanomedicines that are promising therapeutic approaches for various diseases have the potential to create a paradigm shift in endometriosis management. For the first time, the available reports and achievements in the field of endometriosis nanomedicine are critically evaluated, and a summary of how nanoparticle‐based systems can improve endometriosis treatment and diagnosis is provided. Parallels between cancer and endometriosis are also drawn to understand whether some fundamental principles of the well‐established cancer nanomedicine field can be adopted for the development of novel nanoparticle‐based strategies for endometriosis. This review provides the state of the art of endometriosis nanomedicine and perspective for researchers aiming to realize and exploit the full potential of nanoparticles for treatment and imaging of the disorder. Abstract : This review article outlines the potential of nanomedicine for diagnosis and treatment of endometriosis, a gynecological disease characterized by the abnormal growth of endometrial tissue outside the uterus. The up‐to‐date knowledge and developments in the field of endometriosis nanomedicine are critically overviewed. In addition, this work discusses whether some fundamental principles of cancer nanomedicine can be adapted for endometriosis.