Antiphospholipid syndrome leading to paradoxical embolus and stroke via secundum atrial septal defect. Issue 3 (16th March 2021)

• Record Type: Journal Article
• Authors: Campbell, Amy; Kanodia, Avinash Kumar; Gingles, Christopher Robert; Chandrashekar, Harinath
• Is Part Of: BMJ case reports. Volume 14:Issue 3(2021)
• Publication Date: 2021-03-16
• Subjects: stroke -- interventional cardiology; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2020-239674
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : We have presented a case of a 22-year-old man, presenting with cerebral infarct, subsequently found to have antiphospholipid syndrome (APS), deep venous thrombosis, pulmonary embolism and atrial septal defect (ASD), thereby confirming the presence of infarct due to paradoxical embolism in this patient. The importance of ASD in the patients of APS, resulting in paradoxical embolism is debatable, with recent studies undermining its importance. We have demonstrated that it does indeed happen. This would have implications in the risk assessment and management of ASD in such patients. This case report is intended to serve as a reminder of this association and the need to perform further research in this area.