A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation. (30th November 2011)

• Record Type: Journal Article
• Authors: Fischer, C.; Rybakowski, C.; Ferdynus, C.; Sagot, P.; Gouyon, J. B.
• Other Names: Dargaville Peter A. Academic Editor.
• Is Part Of: International journal of pediatrics. Volume 2012(2012)
• Publication Date: 2011-11-30
• Subjects: Pediatrics -- Periodicals; 618.92
• DOI: 10.1155/2012/321545
• Languages: English
• ISSNs: 1687-9740

Abstract

Abstract : The epidemiology of meconium aspiration syndrome (MAS) in term neonates is described in a population-based retrospective study of data recorded for all births from 2000 to 2007 in a French region (Burgundy). Of the 132 884 eligible term newborns, the rate of meconium-stained amniotic fluid (MSAF) was 7.93%. The prevalence of severe MAS was 0.067% in the overall population. MAS rate was 0.11% at 37-38 weeks of gestation (WG), 0.20% at 39–41 WG, and 0.49% at 42-43 WG. Factors independently associated with severe MAS were identified by a case-control study, that is, thick meconium amniotic fluid, fetal tachycardia, Apgar score ≤3 at 1 minute, and birth in a level III facility. Our results confirm the high prevalence of MSAF after 37 WG but also show the low frequency of severe MAS in a period corresponding to the new international recommendations on the management of birth with MSAF.