Bioactivities of Compounds from Elephantopus scaber, an Ethnomedicinal Plant from Southwest China. (19th May 2014)

• Record Type: Journal Article
• Authors: Wang, Jianjun; Li, Ping; Li, Baosai; Guo, Zhiyong; Kennelly, Edward J.; Long, Chunlin
• Other Names: Wu Shi-Biao Academic Editor.
• Is Part Of: Evidence-based complementary and alternative medicine. Volume 2014(2014)
• Publication Date: 2014-05-19
• Subjects: Alternative medicine -- Periodicals; 615.505
• DOI: 10.1155/2014/569594
• Languages: English
• ISSNs: 1741-427X

Abstract

Abstract : Elephantopus scaber is an ethnomedicinal plant used by the Zhuang people in Southwest China to treat headaches, colds, diarrhea, hepatitis, and bronchitis. A new δ -truxinate derivative, ethyl, methyl 3, 4, 3′, 4′-tetrahydroxy- δ -truxinate (1 ), was isolated from the ethyl acetate extract of the entire plant, along with 4 known compounds. The antioxidant activity of these 5 compounds was determined by ABTS radical scavenging assay. Compound 1 was also tested for its cytotoxicity effect against HepG2 by MTT assay (IC 50 = 60 μ M), and its potential anti-inflammatory, antibiotic, and antitumor bioactivities were predicted using target fishing method software.