Choroidal Structural Changes in Patients with Birdshot Chorioretinopathy. (17th February 2021)

• Record Type: Journal Article
• Authors: Bousquet, Elodie; Khandelwal, Neha; Séminel, Marie; Mehanna, Chadi; Salah, Sawsen; Eymard, Pauline; Bodin Hassani, Slim; Monnet, Dominique; Brezin, Antoine; Agrawal, Rupesh
• Is Part Of: Ocular immunology and inflammation. Volume 29:Number 2(2021)
• Page Start: 346
• Page End: 351
• Publication Date: 2021-02-17
• Subjects: Birdshot chorioretinopathy -- choroid -- choroidal vascularity index -- macular edema -- papillitis; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2019.1681472
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose : To assess the choroidal vascularity index (CVI) in birdshot chorioretinopathy (BSCR) patients. Methods : The CVI was calculated as the ratio of luminar area to the total subfoveal choroidal area on enhanced-depth imaging optical coherence tomography. Intraocular inflammation was defined by the presence of macular edema and/or vitritis and/or vasculitis and/or papillitis. Results : Eighty BSCR patients and 22 healthy controls were included. Foveal choroidal thickness was lower in the BSCR compared with the control group ( p < 0.001). CVI was not different between the two groups. CVI was significantly higher in BSCR patients with inflammatory activity ( p = 0.004). Using a multivariate linear regression model, longer disease duration was associated with lower CVI ( p = 0.038), whereas the presence of papillitis was associated with a higher CVI ( p = 0.003). Conclusions : The CVI was not different between the BSCR and the control group. However, the CVI may be used as a new tool for monitoring inflammatory activity in BSCR.