Uterine PEComa initially misdiagnosed as a leiomyoma: Sonographic findings and review of the literature. Issue 5 (16th November 2020)

• Record Type: Journal Article
• Authors: Fontana, Enrico; Savelli, Luca; Alletto, Andrea; Seracchioli, Renato
• Is Part Of: Journal of clinical ultrasound. Volume 49:Issue 5(2021)
• Page Start: 492
• Page End: 497
• Publication Date: 2020-11-16
• Subjects: Doppler -- leiomyoma -- perivascular epithelioid cell tumor -- ultrasound -- uterus; Ultrasonics in medicine -- Periodicals; 616.07543
• DOI: 10.1002/jcu.22950
• Languages: English
• ISSNs: 0091-2751

Abstract

Abstract: Perivascular epithelioid cell neoplasms (PEComas) are rare mesenchymal tumors with malignant potential that arise from gynecological organs in up to 25% of cases. The lack of data regarding the preoperative US features of uterine PEComas is reflected by the frequent misdiagnosis with leiomyomas. We describe the sonographic appearance of a richly vascularized cervical PEComa mimicking a myoma and report the analysis of six additional cases in the literature with a description of their ultrasound features. Most cases involved a single lesion arising from the uterine cervix with a rapid growth pattern, regular margins, heterogeneous echogenicity, absence of shadowing, and moderate‐to‐rich vascularity.