Determination of natural phenolic compounds of Ferula longipedunculata Peşmen and assessment their antioxidant and anticholinesterase potentials. Issue 10 (19th May 2021)

• Record Type: Journal Article
• Authors: Karakaya, Songul; Koca, Mehmet; Sytar, Oksana; Duman, Hayri
• Is Part Of: Natural product research. Volume 35:Issue 10(2021)
• Page Start: 1654
• Page End: 1656
• Publication Date: 2021-05-19
• Subjects: Antioxidants: anticholinesterase -- Apiaceae -- Ferula longipedunculata -- phenolics; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1619728
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: The paper reports anticholinesterase and antioxidant activities of extracts, fractions from aerial parts, roots, flowers, fruits of Ferula longipedunculata Peş men (Apiaceae). Phenolic content, antioxidant activities of samples were carried out using Folin-Ciocalteu, DPPH, TBA methods. Anticholinesterase activity was actualised through Ellman's method. The utmost and least total phenolic content were detected in root MeOH extract (36.4 mg GAE g −1 DW) and aerial part (23.74 mg GAE g −1 DW), respectively. Hexane fraction of root exhibited significant inhibition against AChE (37.99%) and BuChE (81.66%) at 20 μg/mL as well as remarkable antioxidant and anticholinesterase activities. However, investigations on roots will be substantial for improved usage of F. longipedunculata for pharmaceutical and food search needs. Graphical Abstract: