Sleep and puberty. (April 2021)

• Record Type: Journal Article
• Authors: Lucien, Janet N.; Ortega, Madison T.; Shaw, Natalie D.
• Is Part Of: Current opinion in endocrine and metabolic research. Volume 17(2021)
• Page Start: 1
• Page End: 7
• Publication Date: 2021-04
• Subjects: Sleep -- Puberty -- Narcolepsy -- Melatonin -- Delta power; Endocrine glands -- Diseases -- Periodicals; Metabolism -- Disorders -- Periodicals; Endocrine System Diseases; Metabolic Diseases; Endocrine glands -- Diseases; Metabolism -- Disorders; Periodical; Electronic journals; Periodicals; Electronic journals; 616.4
• DOI: 10.1016/j.coemr.2020.09.009
• Languages: English
• ISSNs: 2451-9650

Abstract

Abstract: In 1976, Boyar et al made the seminal observation that during the early stages of puberty, there is a sleep-specific augmentation of pulsatile luteinizing hormone secretion. Building on this tantalizing association between sleep and the reawakening of the neuro-reproductive axis, a number of investigators have since mapped the dynamic relationship between sleep and reproductive hormones across the pubertal transition. In this review, we focus on the complex, reciprocal relationship between sleep and reproductive hormones during adolescence, as well as on the potential effects of melatonin and orexin on gonadotropin-releasing hormone activity in children with chronic insomnia and narcolepsy, respectively. Given the important interaction between the reproductive and somatotropic axes during puberty, we end with a discussion of sleep and growth hormone secretion in children.