Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections. (29th April 2013)

• Record Type: Journal Article
• Authors: Henao-Martínez, Andrés F.; Castillo-Mancilla, José R.; Barron, Michelle A.; Nichol, Aran Cunningham
• Other Names: Gibert C. L. Academic Editor.; Palazzi D. L. Academic Editor.
• Is Part Of: Case reports in infectious diseases. Volume 2013(2013)
• Publication Date: 2013-04-29
• Subjects: Communicable diseases -- Periodicals; Communicable diseases -- Case studies -- Periodicals; Communicable Diseases; Infectious Disease Medicine; Communicable diseases; Electronic journals; Periodicals; Case studies; Periodicals; 616.9
• DOI: 10.1155/2013/589490
• Languages: English
• ISSNs: 2090-6625

Abstract

Abstract : Treatment of Scedosporium apiospermum central nervous system (CNS) infection typically consists of an azole in combination with surgical debridement. This approach requires prolonged treatment and carries a high associated mortality. We present two cases of the successful treatment of S. apiospermum CNS infections with the combination of voriconazole and terbinafine.