Diagnostic use of fine‐needle aspiration cytology and core‐needle biopsy in head and neck sarcomas. Issue 6 (9th March 2021)

• Record Type: Journal Article
• Authors: Sheppard, Sean C.; Borner, Urs; Wartenberg, Martin; Giger, Roland; Nisa, Lluís
• Is Part Of: Head & neck. Volume 43:Issue 6(2021)
• Page Start: 1939
• Page End: 1948
• Publication Date: 2021-03-09
• Subjects: core‐needle biopsy -- diagnostic value -- fine‐needle aspiration cytology -- head and neck sarcoma -- systematic review of published cases; Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.26670
• Languages: English
• ISSNs: 1043-3074

Abstract

Abstract: The diagnostic role of fine‐needle aspiration cytology (FNAC) and core‐needle biopsy (CNB) has not been comprehensively assessed in head and neck sarcomas. A systematic review of published cases (1990–2020) was conducted. Diagnostic performance of both FNAC/CNB to determine tumor dignity and histopathological diagnosis was calculated. One hundred and sixty‐eight cases were included for which FNAC ( n = 156), CNB ( n = 8), or both ( n = 4) were used. Predominant histologies were skeletal muscle, chondrogenic and vascular sarcomas. FNAC correctly assessed dignity in 76.3% and histology in 45% of cases. Dignity was significantly better for vascular tumors, metastatic and recurrent specimens, and worse for chondrogenic sarcomas. CNB showed a 92% accuracy to identify dignity and 83% for histopathology. FNAC and CNB are useful methods for the diagnosis of head and neck sarcomas, particularly well‐suited in the context of recurrent or metastatic disease. The role of CNB remains largely unexplored for this indication.