Effect of a single bout of morning or afternoon exercise on glucose fluctuation in young healthy men. Issue 7 (27th April 2021)

• Record Type: Journal Article
• Authors: Tanaka, Yoshiaki; Ogata, Hitomi; Park, Insung; Ando, Akira; Ishihara, Asuka; Kayaba, Momoko; Yajima, Katsuhiko; Suzuki, Chihiro; Araki, Akihiro; Osumi, Haruka; Zhang, Simeng; Seol, Jaehoon; Takahashi, Keigo; Nabekura, Yoshiharu; Satoh, Makoto; Tokuyama, Kumpei
• Is Part Of: Physiological reports. Volume 9:Issue 7(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-04-27
• Subjects: continuous glucose monitoring -- exercise timing -- glucose fluctuation; Physiology -- Periodicals; 571
• DOI: 10.14814/phy2.14784
• Languages: English
• ISSNs: 2051-817X

Abstract

Abstract: The timing of exercise plays an important role in the effect of the exercise on physiological functions, such as substrate oxidation and circadian rhythm. Exercise exerts different effects on the glycemic response to exercise and meal intake depending on when the exercise performed. Here, we comprehensively investigated the effects of the timing (morning or afternoon) of exercise on glucose fluctuation on the basis of several indices: glycemic variability over 24 h (24‐h SD), J‐index, mean amplitude of glucose excursions (MAGE), continuous overall net glycemic action (CONGA), and detrended fluctuation analysis (DFA). Eleven young men participated in 3 trials in a repeated measures design in which they performed a single bout of exercise at 60% of their maximal oxygen uptake for 1 h beginning either at 7:00 (morning exercise), 16:00 (afternoon exercise), or no exercise (control). Glucose levels were measured using a continuous glucose monitoring system (CGMs). Glucose fluctuation was slightly less stable when exercise was performed in the afternoon than in the morning, indicated by higher CONGA at 2 h and α2 in DFA in the afternoon exercise trial than in the control trial. Additionally, decreased stability in glucose fluctuation in the afternoon exercise trial was supported by the descending values of the other glucose fluctuation indices in order from the afternoon exercise, morning exercise, and control trials. Meal tolerance following exercise was decreased after both exercise trials. Glucose levels during exercise were decreased only in the afternoon exercise trial, resulting in less stable glucose fluctuations over 24 h. Abstract : Comprehensive analyses of multiple indices revealed that the effects of exercise on glucose fluctuation depends on the timing of the exercise. Glucose fluctuation was slightly less stable when exercise was performed in afternoon with higher insulin levels (red) than in morning with lower insulin levels (blue). The effect of differences in the timing of exercise on glucose fluctuation may be due to differences in glucose level changes during exercise.