Metal-free visible-light-induced aerobic oxidation of α-diazoesters leading to α-ketoesters in air. Issue 9 (2nd March 2021)

• Record Type: Journal Article
• Authors: Liu, Ruisheng; Liu, Qishun; Meng, Haoran; Ding, Hongyu; Hao, Jindong; Ji, Zhongyin; Yue, Huilan; Wei, Wei
• Is Part Of: Organic chemistry frontiers. Volume 8:Issue 9(2021)
• Page Start: 1970
• Page End: 1975
• Publication Date: 2021-03-02
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d0qo01587c
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A metal-free and visible-light-induced strategy has been established for the construction of α-ketoesters via aerobic oxidation of α-diazoesters with dioxygen in air at room temperature. Abstract : A metal-free and visible-light-promoted strategy has been achieved for the construction of α-ketoesters via aerobic oxidation of α-diazoesters with dioxygen in air at room temperature. Using cheap, readily available Eosin Y as the photocatalyst and O2 (air) as the green oxidant, the present protocol offers a mild and efficient approach to a wide range of α-ketoesters in moderate to good yields. Preliminary mechanistic studies suggested that photo-excited singlet oxygen was involved in the present reaction system.