Overview of SARS-CoV-2 infection in adults living with HIV. Issue 5 (May 2021)

• Record Type: Journal Article
• Authors: Ambrosioni, Juan; Blanco, José Luis; Reyes-Urueña, Juliana M; Davies, Mary-Ann; Sued, Omar; Marcos, Maria Angeles; Martínez, Esteban; Bertagnolio, Silvia; Alcamí, Jose; Miro, Jose M; Ambrosioni, Juan; Blanco, Jose L.; de la Mora, Lorena; Garcia-Alcaide, Felipe; González-Cordón, Ana; Inciarte, Alexis; Laguno, Montserrat; Leal, Lorna; Martínez-Chamorro, Esteban; Martínez-Rebollar, María; Miró, José M; Rojas, Jhon F.; Torres, Berta; Mallolas, Josep; Albiac, Laia; Agöero, Daiana L.; Bodro, Marta; Cardozo, Celia; Chumbita, Mariana; García, Nicol; García-Vidal, Carolina; Hernández-Meneses, Marta M.; Herrera, Sabina; Linares, Laura; Moreno, Antonio; Morata, Laura; Martínez-Martínez, Jose A.; Puerta, Pedro; Rico, Verónica; Soriano, Alex; Martínez, Mikel; Mosquera, María del Mar; Marcos, Maria A.; Vila, Jordi; Tuset, Montse; Soy, Dolors; Vilella, Anna; Almuedo, Alex; Pinazo, María J.; Muñoz, Jose;
• Is Part Of: Lancet. Volume 8:Issue 5(2021)
• Page Start: e294
• Page End: e305
• Publication Date: 2021-05
• Subjects: HIV (Viruses) -- Periodicals; HIV infections -- Periodicals; AIDS (Disease) -- Periodicals; 616.9792
• DOI: 10.1016/S2352-3018(21)00070-9
• Languages: English
• ISSNs: 2405-4704

Abstract

Summary: Around 2·5 million deaths and more than 110 million COVID-19 cases have been reported globally. Although it initially appeared that HIV infection was not a risk factor for COVID-19 or more severe disease, more recent large studies suggest that people living with HIV (particularly with low CD4 cell counts or untreated HIV infection) might have a more severe clinical course than those who are HIV-negative. Moreover, the COVID-19 pandemic has disrupted HIV prevention and treatment services worldwide, creating huge challenges to the continuity of essential activities. We have reviewed the most relevant features of COVID-19 in people living with HIV and highlighted topics where further research is required.