Improved method for tuberculocidal and mycobactericidal activity testing of disinfectants based on the European Standard EN 14348. (May 2021)

• Record Type: Journal Article
• Authors: Brill, F.H.H.; Lenz, J.; Lach, C.; Radischat, N.; Paßvogel, L.; Goroncy-Bermes, P.; Gabriel, H.; Steinmann, J.; Steinhauer, K.
• Is Part Of: Journal of hospital infection. Volume 111(2021)
• Page Start: 176
• Page End: 179
• Publication Date: 2021-05
• Subjects: Tuberculosis -- Disinfectants -- Activity testing -- Tuberculocidal -- Mycobacteria; Cross infection -- Periodicals; Cross infection -- Prevention -- Periodicals; Nosocomial infections -- Periodicals; Nosocomial infections -- Prevention -- Periodicals; Cross Infection -- Periodicals; Cross Infection -- prevention & control -- Periodicals; Infection Control -- Periodicals; Electronic journals; 614.44
• DOI: 10.1016/j.jhin.2021.02.008
• Languages: English
• ISSNs: 0195-6701

Abstract

Summary: Safe measurements to prevent the transmission of (multidrug-resistant) mycobacteria such as disinfection are essential in healthcare settings. In Europe chemical disinfectants are tested for their tuberculocidal and mycobactericidal efficacy by the internationally accepted test procedure described in EN 14348. However, especially for amine-based disinfectants, invalid results may occur by this procedure due to insufficient neutralization. In this multi-laboratory study the procedure described in EN 14348 was optimized by a combination of chemical neutralization and membrane filtration in order to obtain a valid and secure method especially for amine-based disinfectants.