An unexpected case of Cardiobacterium valvarum prosthetic arthritis without cardiac lesions: Case report and literature review. Issue 5 (May 2021)

• Record Type: Journal Article
• Authors: Koizumi, Yusuke; Ohno, Tomoko; Takada, Takuya; Sakanashi, Daisuke; Nakamura, Akiko; Yamada, Atsuko; Asai, Nobuhiro; Shiota, Arufumi; Hagihara, Mao; Yamagishi, Yuka; Suematsu, Hiroyuki; Deie, Masataka; Mikamo, Hiroshige
• Is Part Of: Journal of infection and chemotherapy. Volume 27:Issue 5(2021)
• Page Start: 747
• Page End: 750
• Publication Date: 2021-05
• Subjects: Prosthetic arthritis -- HACEK -- Modified Levinthal medium -- 16S rRNA sequence analysis -- Infective endocarditis; Chemotherapy -- Periodicals; Infection -- Periodicals; Communicable diseases -- Chemotherapy -- Periodicals; 615.5805
• DOI: 10.1016/j.jiac.2020.12.006
• Languages: English
• ISSNs: 1341-321X

Abstract

Abstract: We report a case of prosthetic arthritis caused by Cardiobacterium valvarum, which has been exclusively reported to cause intravascular infections. A 81-year-old Japanese female complained prosthetic knee joint pain. Arthrocentesis cultured no pathogen, and surgical replacement of the implant surface was performed. Modified Levinthal medium culture and 16S rRNA sequencing has finally led to diagnosis of C. valvarum prosthetic knee arthritis without cardiac lesions. Fastidious bacteria such as C. valvarum can be candidate pathogens of orthopedic infections whose causative agents are sometimes unidentified. Further development of molecular diagnostics is expected, but also the importance of conventional methods should be noted.