Diffusion sensitivity enhancement filter for raw DWIs. Issue 7 (10th September 2018)

• Record Type: Journal Article
• Authors: Mathew, Joshin John; James, Alex; Kesavadas, Chandrasekhar; Paul, Joseph Suresh
• Is Part Of: IET computer vision. Volume 12:Issue 7(2018)
• Page Start: 950
• Page End: 956
• Publication Date: 2018-09-10
• Subjects: biomedical MRI -- brain -- medical image processing -- biodiffusion; nonlinear three-dimensional neighbourhood operation -- weighted average representative -- enhanced DWI -- processed images -- physical diffusion -- resulting improvements -- filtering process -- unprocessed diffusion tensor imaging -- diffusion sensitivity enhancement filter -- raw DWIs -- post-processing filter -- larger intensity changes -- abrupt transition -- local diffusivity -- raw diffusion weighted image volumes -- weights; Computer vision -- Periodicals; Pattern recognition systems -- Periodicals; 006.37
• DOI: 10.1049/iet-cvi.2018.5213
• Languages: English
• ISSNs: 1751-9632

Abstract

Abstract : In this study, a post‐processing filter to enhance diffusion sensitivity, resulting in larger intensity changes in regions with the abrupt transition of local diffusivity in raw diffusion weighted image (DWI) volumes. Weights computed using a non‐linear three‐dimensional neighbourhood operation are assigned to each voxel within the neighbourhood, with the weighted average representative of the enhanced DWI. The processed images exhibit better distinction among regions with differing levels of physical diffusion. While the resulting improvements in diffusion sensitivity are highlighted with the help of colour maps, parametric maps, and tractography, implications of the filtering process to recover missing information is illustrated in terms of ability to restore portions of fibre tracts which are otherwise absent in the unprocessed diffusion tensor imaging. Quantitative evaluation of the filtering process is performed using a metric representative of the estimated b ‐value, which is the consolidation machine parameters used for DWI acquisition.